Key Publications

Thomas Madsen, Marcel Klaassen, Nynke Raven, Antoine M. Dujon, Geordie Jennings, Frédéric Thomas, Rodrigo Hamede, Beata Ujvari. Transmissible cancer and longitudinal telomere dynamics in Tasmanian devils (Sarcophilus harrisii). Molecular Ecology. https://doi.org/10.1111/mec.16721.

Justine Boutry, Sophie Tissot, Narimène Mekaoui, Antoine M. Dujon, Jordan Meliani, Rodrigo Hamede, Beata Ujvari, Aurora M. Nedelcu, Jácint Tokolyi, Frédéric Thomas. Tumors alter life history traits in the freshwater cnidarian, Hydra oligactis. iScience. https://doi.org/10.1016/j.isci.2022.105034.

Frédéric Thomas, Antoine M. Dujon, Beata Ujvari, Catherine Alix-Panabières. Nocturnal circulating tumor cells: The ultimate selective filter in cancer progression? Med. https://doi.org/10.1016/j.medj.2022.07.005.

Gábor Valcz, Beáta Újvári, Edit I. Buzás, et al. Small extracellular vesicle DNA-mediated horizontal gene transfer as a driving force for tumor evolution: Facts and riddles. Frontiers in Oncology. https://doi.org/10.3389/fonc.2022.945376.

Antoine M. Dujon, Justine Boutry, Sophie Tissot, Jordan Meliani, Lena Guimard, Océane Rieu, Beata Ujvari, Frédéric Thomas. A review of the methods used to induce cancer in invertebrates to study its effects on the evolution of species and ecosystem functioning. Methods in Ecology and Evolution. https://doi.org/10.1111/2041-210X.13938.

Sophie Tissot, Anne-Lise Gérard, Justine Boutry, Antoine M. Dujon, Tracey Russel, Hannah Siddle, Aurélie Tasiemski, Jordan Meliani, Rodrigo Hamede, Benjamin Roche, Beata Ujvari and Frédéric Thomas. Transmissible Cancer Evolution: The Under-Estimated Role of Environmental Factors in the “Perfect Storm” Theory. Pathogens. https://doi.org/10.3390/pathogens11020241.

Antoine M. Dujon, Justine Boutry, Sophie Tissot, Jean-François Lemaître, Amy M. Boddy, Anne-Lise Gérard, Alexandra Alvergne, Audrey Arnal, Orsolya Vincze, Delphine Nicolas, Mathieu Giraudeau, Marina Telonis-Scott, Aaron Schultz, Pascal Pujol, Peter A. Biro, Christa Beckmann, Rodrigo Hamede, Benjamin Roche, Beata Ujvari and Frédéric Thomas. Cancer Susceptibility as a Cost of Reproduction and Contributor to Life History Evolution. Frontiers in Ecology and Evolution. https://doi.org/10.3389/fevo.2022.861103.

Beata Ujvari, Nynke Raven, Thomas Madsen, Marcel Klaassen, Antoine M. Dujon, Aaron G. Schultz, Leonard Nunney, Jean-François Lemaître, Mathieu Giraudeau, Frédéric Thomas. Telomeres, the loop tying cancer to organismal life-histories. Molecular Ecology. https://doi.org/10.1111/mec.16488.

Peter A Biro, Frédéric Thomas, Beata Ujvari, Christa Beckmann. A novel perspective suggesting high sustained energy expenditure may be net protective against cancer. Evolution Medicine and Public Health. https://doi.org/10.1093/emph/eoac012.

Sophia Belkhir; Rodrigo Hamede; Frédéric Thomas; Beata Ujvari; Antoine M. Dujon. Season, weight, and age, but not transmissible cancer, affect tick loads in the endangered Tasmanian devil. Infection, Genetics and Evolution. https://doi.org/10.1016/j.meegid.2022.105221.

Nynke Raven, Marcel Klaassen, Thomas Madsen, Frédéric Thomas, Rodrigo K. Hamede, Beata Ujvari. Transmissible cancer influences immune gene expression in an endangered marsupial, the Tasmanian devil (Sarcophilus harrisii). Molecular Ecology. https://doi.org/10.1111/mec.16408.

Orsolya Vincze, Fernando Colchero, Jean-Francois Lemaître, Dalia A. Conde, Samuel Pavard, Margaux Bieuville, Araxi O. Urrutia, Beata Ujvari, Amy M. Boddy, Carlo C. Maley, Frédéric Thomas & Mathieu Giraudeau. Cancer risk across mammals. Nature. https://doi.org/10.1038/s41586-021-04224-5.

Justine Boutry, Sophie Tissot, Beata Ujvari, Jean-Pascal Capp, Mathieu Giraudeau, Aurora M. Nedelcu, Frédéric Thomas. The evolution and ecology of benign tumors. Biochimica et Biophysica Acta (BBA) – Reviews on Cancer. https://doi.org/10.1016/j.bbcan.2021.188643.

Flora Gouzerh, Jean-Marie Bessière, Beata Ujvari, Frédéric Thomas , Antoine M Dujon, Laurent Dormont. Odors and cancer: Current status and future directions. Biochimica Et Biophysica Acta-reviews On Cancer. https://doi.org/10.1016/j.bbcan.2021.188644.

Francesco Catania, Beata Ujvari, Benjamin Roche, Jean-Pascal Capp and Frédéric Thomas. Bridging Tumorigenesis and Therapy Resistance With a Non-Darwinian and Non-Lamarckian Mechanism of Adaptive Evolution. Frontiers in Oncology. https://doi.org/10.3389/fonc.2021.732081.

Antoine M. Dujon, Gail Schofield, Roberto M. Venegas, Frédéric Thomas and Beata Ujvari. Sea Turtles in the Cancer Risk Landscape: A Global Meta-Analysis of Fibropapillomatosis Prevalence and Associated Risk Factors. Pathogens. https://doi.org/10.3390/pathogens10101295.

Antoine M. Dujon, Joel S. Brown, Delphine Destoumieux-Garzón, Marion Vittecoq, Rodrigo Hamede, Aurélie Tasiemski, Justine Boutry ,Sophie Tissot, Catherine Alix-Panabieres, Pascal Pujol, François Renaud, Frédéric Simard ,Benjamin Roche, Beata Ujvari, Frédéric Thomas. On the need for integrating cancer into the One Health perspective. Evolutionary Applications. https://doi.org/10.1111/eva.13303.

Antoine M. Dujon, Marion Vittecoq, Georgina Bramwell, Frédéric Thomas, Beata Ujvari. Machine learning is a powerful tool to study the effect of cancer on species and ecosystems. Methods in Ecology and Evolution. https://doi.org/10.1111/2041-210X.13703.

Justine Boutry; Juliette Mistral; Laurent Berlioz; Alexander Klimovich; Jácint Tökölyi; Laura Fontenille; Beata Ujvari; Antoine M. Dujon; Mathieu Giraudeau; Frédéric Thomas. Tumors (re)shape biotic interactions within ecosystems: Experimental evidence from the freshwater cnidarian Hydra. Science of The Total Environment. https://doi.org/10.1016/j.scitotenv.2021.149923.

Jean-Pascal Capp, Joel S. Brown, Pascal Pujol, Robert A. Gatenby, Beata Ujvari, Catherine Alix-Panabières and Frédéric Thomas. Is There One Key Step in the Metastatic Cascade? Cancers. https://doi.org/10.3390/cancers13153693.

Gail Schofield, Liam C. D. Dickson, Lucy Westover, Antoine M. Dujon and Kostas A. Katselidis. COVID-19 disruption reveals mass-tourism pressure on nearshore sea turtle distributions and access to optimal breeding habitat. Evolutionary Applications. https://doi.org/10.1111/eva.13277.

Jean-Pascal Capp ,Aurora M Nedelcu, Antoine M Dujon, Benjamin Roche, Francesco Catania, Beata Ujvari, Catherine Alix-Panabières and Frédéric Thomas. Does Cancer Biology Rely on Parrondo’s Principles? Cancers. https://doi.org/10.3390/cancers13092197.

Georgina Bramwell, Aaron G. Schultz, Craig D. H. Sherman, Mathieu Giraudeau, Frédéric Thomasb, Beata Ujvari, Antoine M Dujon. A review of the potential effects of climate change on disseminated neoplasia with an emphasis on efficient detection in marine bivalve populations. Science of The Total Environment. https://doi.org/10.1016/j.scitotenv.2021.145134.

Jean-Pascal Capp, James DeGregori, Aurora M Nedelcu, Antoine M Dujon, Justine Boutry, Pascal Pujol, Catherine Alix-Panabières, Rodrigo Hamede, Benjamin Roche, Beata Ujvari, Andriy Marusyk, Robert Gatenby, Frédéric Thoma. Group phenotypic composition in cancer. eLife. https://doi.org/10.7554/eLife.63518.

Ciara Baines; Adelaide Lerebours; Frederic Thomas; Jerome Fort; Randel Kreitsberg; Sophie Gentes; Richard Meitern; Lauri Saks; Beata Ujvari; Mathieu Giraudeau; Tuul Seppa. Linking pollution and cancer in aquatic environments: A review. Environment International. https://doi.org/10.1016/j.envint.2021.106391.

Antoine M. Dujon, Athena Aktipis, Catherine Alix‐Panabières, [……….], Frédéric Thomas & Beata Ujvari. Identifying key questions in the ecology and evolution of cancer. Evolutionary Applications. https://doi.org/10.1111/eva.13190.

Austin H. Patton, Matthew F. Lawrance, Mark J. Margres, Christopher P. Kozakiewicz, Rodrigo Hamede, et al. A transmissible cancer shifts from emergence to endemism in Tasmanian devils. Science. https://doi.org/10.1126/science.abb9772.

Peter A. Biro, Frédéric Thomas, Beata Ujvari, Christa Beckmann. Can Energetic Capacity Help Explain Why Physical Activity Reduces Cancer Risk? Trends in Cancer. https://doi.org/10.1016/j.trecan.2020.06.001.

Lemaître, J.F., Pavard, S., Giraudeau, M., Vincze, O., Jennings, G, Hamede, R., Ujvari, B, Thomas, F. Eco-evolutionary perspectives of the dynamic relationships linking senescence and cancer. Functional Ecology. https://doi.org/10.1111/1365-2435.13394.

Giraudeau, M., Sepp, T., Ujvari, B., renaud, F., Tasiemski, A., Roche, B., Capp, J.P. & Thomas F. 2019. Differences in mutational processes and intratumour heterogeneity between organs: the local selective filter hypothesis. Evolution, Medicine and Public health. https://doi.org/10.1093/emph/eoz017.

Dheilly, N.M., Ewald, P., Brindley, J., Raina, J., Fichorova, N. & Thomas, F. Parasite-microbe-host interactions and cancer risk. PLoS Pathogens. https://doi.org/10.1371/journal.ppat.1007912.

Sepp T, Ujvari B, Ewald PW, Thomas F & Giraudeau M. 2019. Urban environment and cancer in wildlife: Available evidence and future research avenues. Proc. R. Soc. B Biol. Sci. https://doi.org/10.1098/rspb.2018.2434.

Thomas, F., Madsen, T., Giraudeau, M., Misse, D., Hamede, R., Vincze, O., Renaud, F., Roche, B. & Ujvari. Transmissible cancer and the evolution of sex. PloS Biol. 2019 June 6. https://doi.org/10.1371/journal.pbio.3000275.

Thomas, F., Kareva, I., Raven, N., Hamede, R., Pujol, P., Roche, B., Ujvari, B. 2018. Evolved dependence to cancer. Trends in Ecology and Evolution. Apr;33(4):269-276. https://doi.org/10.1016/j.tree.2018.01.012.

Dawson, E. H., Bailly, T.P.M, Dos Santos, J., Moreno, C., Devilliers, M., Maroni, B., Sueur, C., Casali, A.,Ujvari, B., Thomas, F., Montagne, J., Mery, F*. 2018. An interaction between cancer progression and social environment in Drosophila. Nature communications. *EQUAL CONTRIBUTION, Monday, September 3. http://dx.doi.org/10.1038/s41467-018-05737-w.

Giraudeau M., Tuul, S., Ujvari, B., Ewald, P.W., Thomas F. May 2018. Human activities might influence oncogenic processes in wild animal populations. Nature Ecology and Evolution. https://doi.org/10.1038/s41559-018-0558-7.

Thomas, F., Donnadieu, E., Charriere, G., Jacqueline, C., Tasiemski, A., Pujol, P., Renaud, F., Roche, B., Hamede, R., Brown, J., Gatenby, R. and Ujvari, B. Oct 2018. Is Adaptive therapy natural? PLoS Biology. https://doi.org/10.1371/journal.pbio.2007066.

Gidoin, C., Ujvari; B., Thomas, F. Roche, B. Dec 2018. How is the evolution of tumour resistance at organ-scale impacted by the importance of the organ for fitness? BMC Evolutionary Biology. https://doi.org/10.1186/s12862-018-1298-7.

Thomas, F., Jacqueline, C. , Tissot, T., Henard, M., Blanchet, S., Loot, G., Dawson, E., Mery, F., Renaud, F., Montagne, J., Beckmann, C., Biro, P.A., Hamede, R. and Ujvari B. 2017. The importance of cancer cells for animal evolutionary ecology. Nature Ecology and Evolution, 1: 1592-1595. https://doi.org/10.1038/s41559-017-0343-z.

Jacqueline C., Brazier L., Faugère D., Renaud F., Thomas F. and Roche B. 2017. Can intestinal microbiota be associated with non-intestinalcancers? Scientific Reports, 7(1) :12722 . https://doi.org/10.1038/s41598-017-11644-9.

Jacqueline, C., Tasiemski, A., Sorci, G., Ujvari, B., Maachi, F, Missé, D., Renaud, F., Ewald, P., Thomas, F. and Roche, B. 2017. Infections and cancer: the “fifty shades of immunity” hypothesis. BMC cancer, 17(1): 257. https://doi.org/10.1186/s12885-017-3234-4.

Thomas, F., Nesse, R., Gatenby, R., Gidouin, C., Renaud, F., Roche, B. & Ujvari, B. 2016. Evolutionary Ecology of Organs: a Missing Link in Cancer Development? Trends in Cancer, 2: 409-414. https://doi.org/10.1016/j.trecan.2016.06.009.

Jacqueline, C., Biro, P., Beckmann, C., Moller, A.P., Renaud, F., Sorci, G. Tasiemski, A., Ujvari, B. and Thomas, F. 2016. Cancer: a disease at the crossroads of trade-offs. Invited Review. Evolutionary Applications. https://doi.org/10.1111/eva.12444.

Arnal, A., Tissot, T., Ujvari, B., Nunney, L., Solary, E., Laplane, L., Bonhomme, F., Vittecoq, M., Tasiemski, A., Renaud, F., Pujol, P. Roche, B. & Thomas , F. 2015. The guardians of inherited oncogenic vulnerabilities. Evolution, 70-1: 1–6. https://doi.org/10.1111/evo.12809.

Ducasse, H., Ujvari, B., Solary, E., Vittecoq, M., Arnal, A., Bernex, F., Pirot, N., Missé, D., Bonhomme, F., Renaud, F., Thomas, F. and Benjamin Roche. 2015. Can Peto’s paradox be used as the null hypothesis to identify the role of evolution in 4 natural resistance to cancer? A critical review. BMC Cancer, 15:792. https://doi.org/10.1186/s12885-015-1782-z.

Vittecoq, M., Ducasse, H., Arnal, A., Moller, A.P., Ujvari, B., Missé, D., Bernex, F., Pirot, N., Lemberger, K., Abadie, J., Labrut, S., Bonhomme, F., Renaud, F., Roche, B. & Thomas, F. 2015. Animal Behaviour and Cancer. Animal Behaviour. 101 19-26. https://doi.org/10.1016/j.anbehav.2014.12.001.

Vittecoq M., Roche B., Daoust S.P., Ducasse H., Misse D. , Abadie J., Labrut S., Renaud F., Gauthier-Clerc M. & Thomas F. 2013. Cancer: a missing link in ecosystem functioning? Trends in Ecology and Evolution, 28:628-635. https://doi.org/10.1016/j.tree.2013.07.005.

Roche B., Sprouffske K., Hbid H., Misse D. & Thomas F. 2013. Peto’s paradox revisited: theoretical evolutionary dynamics of cancer in wild populations. Evolutionary Applications, 6: 109-116. https://dx.doi.org/10.1111%2Feva.12025.

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